Bio! News January 2012 – D

Bio! News
January 2012 – D

By reprogramming Alzheimer patients-derived fibroblasts into pluripotent cells, a research group demonstrated that neurons that grew from these induced pluripotent cells presented higher levels of the pathological markers when compared to control (non-Alzheimer)-derived cells. This may be useful for detecting Alzheimer phenotypes decades before the disease shows up.

Using a mouse model, a research group found that the parallel blooms of Salmonella enterica serovar Typhimurium and commensal E. coli were explained because of the inter-species transfer of the P2 plasmid. During inflammation, high densities of donor Salmonella and acceptor E. coli are attained and this may trigger horizontal gene transfer, along with the P2-colicin- resistance transmission.

Recently, using mass spec information about lipids of Mycobacterium tuberculosis, a resarch group was able to infer a biosynthetic pathway for mycobactins and its regulation by iron. They also discovered two new families of lipids.

A new study, conducted in the Brazilian Cerrado, provides evidence of a new kind of carnivore plants. The plants of the genus Philcoxia grow upon low-nutrient environment and have developed subterranean adhesive leaves that capture and digest nematodes.

A research group has reported the physiological effects of the mushroom-derived hallucinogen psilocybin. Among the effects of the drug are the reduction of blood flow to the medial prefrontal cortex and the posterior cingulate cortices, both involved in the coordination of information in the brain.


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